Endophytic fungi are symbiotically related to plants and spend most of their life cycle within them. In nature, they have a crucial role in plant micro-ecosystem. They are harnessed for their bioactive compounds to counter human health problems and diseases. Endophytic Diaporthe sp. is a widely distributed fungal genus that has garnered much interest within the scientific community. A substantial number of secondary metabolites have been detected from Diaporthe sp. inhabited in various plants. As such, this minireview highlights the potential of Diaporthe sp. as a rich source of bioactive compounds by emphasizing on their diverse chemical entities and potent biological properties. The bioactive compounds produced are of significant importance to act as new lead compounds for drug discovery and development.
Chemistry Section, School of Distance Education, Universiti Sains Malaysia
E-mail : tanwn@usm.my
Senior Lecturer, Chemistry Section, School of Distance Education, Universiti Sains Malaysia, Malaysia
Visiting Fellow, National Yang-Ming University, Taiwan
Senior Engineer, Penang Seagate Industries (M) Sdn Bhd, Malaysia
Chemistry Section, School of Distance Education, Universiti Sains Malaysia
E-mail : kashvintha18@gmail.com
Chemistry Section, School of Distance Education, Universiti Sains Malaysia, Malaysia
AIMST University
The Natural Product Research Laboratory at Chemistry Section, School of Distance Education, Universiti Sains Malaysia focuses on research relating to extraction, isolation, structural elucidation of bioactive compounds from natural products (plants and fungi). Additionally, we also conducting research on chemical profiling/fingerprinting of bioactive extracts using metabolomics approaches.