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2020 December Vol.33 No.4 ISSN 1598-8384

신진과학자

신진과학자 소개

염 진 기 (Jinki Yeom)

서울대학교 의과대 E-mail : jinki.yeom@snu.ac.kr

[학력]

2001.03 - 2006.02
고려대학교 환경생태공학부, 학사
2006.03 - 2008.02
고려대학교 환경생태공학부, 석사
2008.03 - 2011.02
고려대학교 환경생태공학부, 박사

[경력]

2011.03 - 2011.12
고려대학교 환경생태공학부, 박사 후 연구원
2012.02 - 2013.02
한국기초과학지원연구원 서울센터, 박사 후 연구원
2013.04 - 2017.04
Yale University, USA, Postdoctoral Associate
2017.05 - 2019.02
Yale University, USA, Associate Research Scientist
2019.04 - 2020.08
Duke-NUS Medical School, Singapore, 조교수
2020.09 - 현재
서울대학교 의과대학 미생물학교실, 조교수

[주요 연구 관심 분야 소개]

스트레스 조건에서 병원성 세균의 생존 기작 규명
병원성 세균의 병원성 및 항생제 내성 기작 규명
세균의 단백질 분해 기작 연구
숙주 내에서 병원성 세균의 생존 전략 연구

[연구성과 - 논문]

1. Hong, S. W., Kim, J.H., Bae, H.J., Ham, J.S., Yoo, J.G., Chung, K.S., and Oh, M.H., Selection and characterization of broad-spectrum antibacterial substance producing Lactobacillus curvatus PA40 as a potential probiotic for feed additives. Animal Science Journal, 2018.
2. Yeom J, Shao Y, Groisman EA. Small proteins regulate Salmonella survival inside macrophages by controlling degradation of a magnesium transporter. PNAS, 2020.
3. Gao X*, Yeom J*, Groisman EA. The expanded specificity and physiological role of a widespread N-degron recognin. PNAS, 2019. (*Co-first authors)
4. Yeom J, Groisman EA. Activator of one protease transforms into inhibitor of another in response to nutritional signals. Genes Dev, 2019.
5. Yeom J, Pontes MH, Choi J, Groisman EA. A protein that controls the onset of a Salmonella virulence program. EMBO J, 2018.
6. Yeom J, Gao X, Groisman EA. A reduction in adaptor amounts establishes degradation hierarchy among protease substrates. PNAS, 2018.
7. Yeom J, Kyle WJ, Groisman EA. Sequestration from protease adaptor confers differential stability to protease substrate. Mol Cell, 2017.
8. Pontes MH, Yeom J, Groisman EA. reducing ribosome biosynthesis promotes translation during low Mg²⁺ stress. Mol Cell, 2016.
9. Yeom J*, Shin JH*, Yang JY, Kim J, Hwang GS. (1)H NMR-based metabolite profiling of planktonic and biofilm cells in Acinetobacter baumannii 1656-2. PLoS One, 2013. (*Co-first authors)
10. Cui Y, Kim SH, Kim H, Yeom J, Ko K, Park W, Park S. AFM probing the mechanism of synergistic effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) with cefotaxime against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli. PLoS One, 2012.
11. Yeom J, Park W. Biochemical characterization of ferredoxin-NADP(+) reductase interaction with flavodoxin in Pseudomonas putida.BMB Rep, 2012.
12. Yeom J, Park W. Pleiotropic effects of the mioC mutation on the physiology of Pseudomonas aeruginosa PAO1. FEMS Microbiol Lett, 2012.
13. Jung J*, Yeom J*, Han J, Kim J, Park W. Seasonal changes in nitrogen-cycle gene abundances and in bacterial communities in acidic forest soils. J Microbiol, 2012. (*Co-first authors)
14. Yeom J, Lee Y, Park W. ATP-dependent RecG helicase functions in bacterial transcription. J Biol Chem, 2012.
15. Yeom J, Lee Y, Park W. Effects of non-ionic solute stresses on the biofilm formation and lipopolysaccharide production in Escherichia coli O157:H7. Res Microbiol, 2012.
16. Jung J*, Yeom J*, Kim J, Han J, Lim HS, Park H, Hyun S, Park W. Change in gene abundance in the nitrogen biogeochemical cycle with temperature and nitrogen addition in Antarctic soils. Res Microbiol, 2011. (*Co-first authors)
17. Yeom J, Lee Y, Noh J, Jung J, Park J, Seo H, Kim J, Han J, Jeon CO, Kim TS, Park W. Detection of genetically modified microorganisms in soil using the most-probable-number method with multiplex PCR and DNA dot blot. Res Microbiol, 2011.
18. Lee Y, Seo H, Yeom J, Park W. Molecular characterization of the extracellular matrix in a Pseudomonas putida dsbA mutant: implications for acidic stress defense and plant growth promotion. Res Microbiol, 2011.
19. Lee Y*, Yeom J*, Kim J, Jung J, Jeon CO, Park W. Phenotypic and physiological alterations by heterologous acyl-homoserine lactone synthase expression in Pseudomonas putida. Microbiology-sgm, 2010. (*Co-first authors)
20. Yeom J, Imlay JA, Park W. Iron homeostasis affects antibiotic-mediated cell death in Pseudomonas species. J Biol Chem, 2010.
21. Yeom S*, Yeom J*, Park W. NtrC-sensed nitrogen availability is important for oxidative stress defense in Pseudomonas putida KT2440. J Microbiol, 2010. (*Co-first authors)
22. Yeom S*, Yeom J*, Park W. Molecular characterization of FinR, a novel redox-sensing transcriptional regulator in Pseudomonas putida KT2440. Microbiology-sgm, 2010. (*Co-first authors)
23. Kim J, Yeom J, Jeon CO, Park W. Intracellular 2-keto-3-deoxy-6-phosphogluconate is the signal for carbon catabolite repression of phenylacetic acid metabolism in Pseudomonas putida KT2440. Microbiology-sgm, 2009.
24. Yeom J, Jeon CO, Madsen EL, Park W. In vitro and in vivo interactions of ferredoxin-NADP⁺ reductases in Pseudomonas putida. J Biochem, 2009.
25. Yeom J, Jeon CO, Madsen EL, Park W. Ferredoxin-NADP⁺ reductase from Pseudomonas putida functions as a ferric reductase. J Bacteriol, 2009.
26. Lee Y*, Yeom J*, Kang YS, Kim J, Sung JS, Jeon CO, Park W. Molecular characterization of fprB (ferredoxin-NADP⁺ reductase) in Pseudomonas putida KT2440. J Microbiol Biotechnol, 2007. (*Co-first authors)
27. Kim YH, Lee Y, Kim S, Yeom J*, Yeom S, Seok Kim B, Oh S, Park S, Jeon CO, Park W. The role of periplasmic antioxidant enzymes (superoxide dismutase and thiol peroxidase) of the Shiga toxin-producing Escherichia coli O157:H7 in the formation of biofilms. Proteomics, 2006.