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2020 March Vol.33 No.1 ISSN 1598-8384

신진과학자

신진과학자 소개

김 수 정 (Soo-Jung Kim)
김 수 정 (Soo-Jung Kim)

전남대학교 농식품생명공학부 식품공학전공 E-mail : bioksj@jnu.ac.kr

[학력]
  • 1999.03 – 2003.02

    동국대학교, 식물자원학과 & 식품공학과, 학사(농학사 & 공학사)

  • 2003.03 – 2005.02

    서울대학교, 농생명공학부, 식품생명공학전공, 석사(농학석사)

  • 2009.09 – 2014.02

    서울대학교, 농생명공학부, 식품생명공학 전공, 박사 (농학박사)

[경력]
  • 2012.01 – 2012.04

    University of Illinois at Urbana Champaign, Dept. of Food Science and Human Nutrition, 방문연구원

  • 2014.03 – 2017.03

    서울대학교 식품바이오융합연구소, 연수연구원

  • 2017.03 – 2018.07

    Washington University in St. Louis, Dept. of Energy, Environmental and Chemical Engineering, 박사후연구원

  • 2018.08 – 2019.08

    한국생명공학연구원, 합성생물학전문연구단, 연수연구원

  • 2019.09 – 현재

    전남대학교, 농식품생명공학부 식품공학전공, 조교수

주요 연구 관심 분야 소개

  • 식품 내 위험요소(중금속, 식중독균)를 감지할 수 있는 바이오센서 개발
  • 미생물 세포공장을 이용한 고부가가치 식품, 화장품, 의약품 소재 생산
  • GRAS 미생물의 유전자 도구 및 유전자 회로 개발
  • 합성 small RNA (CRISPRi, antisense RNA)를 이용한 미생물 대사 경로 조절
  • 다중오믹스 기반 식품미생물의 특성 분석

연구성과 - 논문

  • 1. JW Kim, YG Lee, SJ Kim, YS Jin, and JH Seo, Deletion of glycerol-3-phosphate dehydrogenase genes improved 2,3-butanediol production by reducing glycerol production in pyruvate decarboxylase-deficient Saccharomyces cerevisiae, Journal of Biotechnology 304(10) 31-37 (2019).
  • 2. SJ Kim, SK Kim, W Seong, SG Woo, H Lee, SJ Yeom, H Kim, DH Lee, and SG Lee, Enhanced (-)-α-bisabolol productivity by efficient conversion of mevalonate in Escherichia coli, Catalysts 9(5) 432 (2019).
  • 3. SK Kim, PK. Yoon, SJ Kim, SG Woo, E Rha, H Lee, SJ Yeom, H Kim, DH Lee, and SG Lee, CRISPR interference-mediated gene regulation in Pseudomonas putida KT2440, Microbial Biotechnology 1-12 (2019).
  • 4. SJ Kim*, M Leong*, MB. Amrofell, YJ Lee, and TS Moon. Modulating responses of toehold switches by an inhibitory hairpin, ACS Synthetic Biology 8(3), 601-605 (2019).
  • 5. YJ Lee*, SJ Kim*, MB. Amrofell* and TS Moon. Establishing a multivariate model for predictable antisense RNA-mediated repression, ACS Synthetic Biology 8(1), 45-56 (2019).
  • 6. YJ Lee, SJ Kimand TS Moon. Multilevel regulation of bacterial gene expression with the combined STAR and antisense RNA system. ACS Synthetic Biology 7(3), 853-865 (2018).
  • 7. SJ Kim*, JE Lee*, DY Lee*, H Park, KH Kim and YC Park. Multi-omic characterization of laboratory-evolved Saccharomyces cerevisiae HJ7-14 with high algal ethanol-producing ability. Applied Microbiology and Biotechnology 102(20), 8989-9002 (2018).
  • 8. YH Cho*, SJ Kim*, JY Kim, DH Lee, K Park, YC Park. Effect of PelB signal sequences on Pfe1 expression and ω-hydroxyundec-9-enoic acid biotransformation in recombinant Escherichia coli. Applied Microbiology and Biotechnology 102(17), 7407-7416 (2018).
  • 9. SJ Kim*, HJ Shim*, JW Kim, YG Lee, YC Park and JH Seo. Enhanced production of 2,3-butanediol production from xylose by combinatorial engineering of xylose metabolic pathway and cofactor regeneration in pyruvate decarboxylase-deficient Saccharomyces cerevisiae. Bioresource Technology 245: 1551-1557 (2017).
  • 10. YH Cho, SJ Kim, HW Kim, JY Kim, JS Gwak, D Chung, KH Kim, K Park and YC Park. Continuous supply of glucose and glycerol enhances biotransformation of ricinoleic acid to (E)-11-(heptanoyloxy) undec-9-enoic acid in recombinant Escherichia coli. Journal of Biotechnology 253: 34-39 (2017).
  • 11. SJ Kim, JW Kim, YG Lee, YC Park and JH Seo. Metabolic engineering of Saccharomyces cerevisiae for 2,3-butanediol production. Applied Microbiology and Biotechnology 101(6): 2241-2250 (2017).
  • 12. YJ Seong, H Park, J Yang, SJ Kim, W Choi, KH Kim and YC Park, Expression of a mutated SPT15 gene in Saccharomyces cerevisiae enhances both cell growth and ethanol production in microaerobic batch, fed-batch and simultaneous saccharification and fermentations. Applied Microbiology and Biotechnology 101(9): 3567-3575 (2017).
  • 13. EJ Choi, JW Kim, SJ Kim, SO Seo, S Lane, YC Park, YS Jin and JH Seo. Enhanced production of 2,3-butanediol in pyruvate decarboxylase-deficient Saccharomyces cerevisiae through optimizing ratio of glucose/galactose. Biotechnology Journal 11(11): 1424-1432 (2016).
  • 14. SE Jo, YJ Seong, HS Lee, SM Lee, SJ Kim, K Park and YC Park. Microaerobic conversion of xylose to ethanol in recombinant Saccharomyces cerevisiae SX6 (MUT) expressing cofactor-balanced xylose metabolic enzymes and deficient in ALD6. Journal of Biotechnology 227: 72-78 (2016).
  • 15. MH Choi, SJ Kim, JW Kim, YC Park and JH Seo. Molecular cloning and expression of Enterobacter aerogenes α-acetolactate decarboxylase in pyruvate decarboxylase-deficient Saccharomyces cerevisiae for efficient 2,3-butanediol production. Process Biochemistry 51(2): 170-176 (2016).
  • 16. HJ Lee, SJ Kim, JJ Yoon, KH Kim, JH Seo and YC Park. Evolutionary engineering of Saccharomyces cerevisiae for efficient conversion of red algal biosugars to bioethanol. Bioresource Technology 191: 445-451 (2015).
  • 17. YH Cho, HJ Lee, JE Lee, SJ Kim, K Park, DY Lee and YC Park. Fast determination of multiple-reaction intermediates for long-chain dicarboxylic acid production by gas chromatography-flame ionization detector. Journal of Microbiology and Biotechnology 25(5): 704-708 (2015).
  • 18. SJ Kim, SO Seo, YC Park, YS Jin and JH Seo. Production of 2,3-butanediol from xylose by engineered Saccharomyces cerevisiae. Journal of Biotechnology 192: 376-382 (2014).
  • 19. DH Lee, SJ Kim and JH Seo. Molecular cloning and characterization of two novel fructose-specific transporters from the osmotolerant and fructophilic yeast Candida magnoliae JH110. Applied Microbiology and Biotechnology 98(8): 3569-3578 (2014).
  • 20. SJ Kim*, SO Seo*, YS Jin and JH Seo. Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresource Technology 146: 274-281 (2013).
  • 21. SJ Kim, MD Kim, JH Choi, SY Kim, YW Ryu and JH Seo. Amplification of 1-deoxy-D-xyluose 5-phosphate (DXP) synthase level increases Coenzyme Q10 production in recombinant Escherichia coli. Applied Microbiology and Biotechnology 72: 982-985 (2006).
  • 22. YC Park, SJ Kim, JH Choi, WH Lee, K Park, M Kawamukai, YW Ryu and JH Seo. Batch and fed-batch production of Coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. Applied Microbiology and Biotechnology 67: 192-196 (2005). (*Denotes equal contribution)

연구성과 - 특허등록

  • 1. 포도당 및 글리세롤을 이용한 유가식 배양을 통한 리시놀레산으로 오메가-하이드록시운덱-9-에논산의 생물전환공정, 박용철, 조용한, 김수정, 대한민국 10-1875564 (2018.07.02.)
  • 2. 아라비노스 이송체를 도입한 효모를 이용한 자일리톨 및 에탄올 생산, 박용철, 이현수, 김수정, 대한민국 10-1843158 (2018.03.22.)
  • 3. Method of producing 2,3-butanediol using recombinant yeast, Jin-Ho Seo, Soo-Jung Kim and Seung-Oh Seo, US9328358 B2, USA (2016.05.03.)
  • 4. 재조합 효모를 이용한 2,3-부탄다이올의 생산방법, 서진호, 김수정, 서승오, 대한민국 10-1590993 (2016.01.27.)
  • 5. 포도당 제한 공급 방식의 유가식 배양을 통한 고생산성 리시놀레산의 생물전환공정, 박용철, 이혜진, 박규상, 조용한, 김수정, 이도엽, 대한민국 10-1548531 (2015.08.25.)