The rise of antimicrobial resistance (AR) is a major threat to global health. The food animal industry contributes to the increasing occurrence of AR. Multiple factors can affect the occurrence and dissemination of AR in the animal industry, including antibiotic use and farm management. Many studies have focused on how the use of antibiotics in food-producing animals has led to the development of AR. However, a few effective mitigating strategies for AR have been developed in food-producing animals, especially those exposed to the environment. The aim of this review is to summarize potential strategies applicable for mitigating AR at the environment-livestock interface.
Associate Professor, Dept. of Animal Sciences & Emerging Pathogens Institute, University of Florida
Assistant professor, Dept. of Animal Sciences & Emerging Pathogens Institute, University of Florida
Postdoc, Dept. of Molecular Microbiology, Washington University in St. Louis, School of Medicine
Ph.D. Dept. of Food Microbiology and Toxicology, University of Wisconsin-Madison, Wisconsin
Awards of Excellence for Graduate Research, Best Doctoral Dissertation Advisor, CALS, University of Florida
University Term Professorship Award, University of Florida
International Educator of the Year Award, CALS, University of Florida
Sigma Xi, Junior Faculty Research Award, University of Florida
Career Development Award, Institute of Food and Agricultural Sciences, University of Florida
The Laboratorian of the Year Award, Florida Association of Food Protection
Berg/Morse Fellowship Award, Washington University in St. Louis, School of Medicine
Postdoctoral Research Associate, Dept. of Animal Sciences & Emerging Pathogens Institute, University of Florida
Ph.D. Dept. of Animal Sciences & Emerging Pathogens Institute, University of Florida
M.S. Dept. of Animal Sciences, University of Florida
Best UF/IFAS Doctor of Philosophy Dissertation Award
My ultimate research goal is to reduce pathogens in animals and humans, focusing on the mitigation of zoonotic pathogens to enhance food safety, to mitigate pathogen transmissions, and to reduce antimicrobial resistance. The research fits under the umbrella of the One Health concept. Basic science focuses on developing understanding of the molecular mechanisms of antimicrobial resistance, colonization, host-microbe interactions, and survival of pathogens in hosts.
i) Microbiology with food safety emphasis, ii) Host-microbe interaction to understand mechanisms that cause disease in hosts, iii) High throughput analyses including whole genome sequencing and metagenomics to identify and understand genetic factors that are required for survival and persistence in hosts and environments, iv) Determination of animal factors that modulate the survival of pathogens during infection, v) Antimicrobial resistance: prevalence, mechanisms of antimicrobial resistance development, and transmission, vi) Development of mitigation strategies for antimicrobial resistance that also leads to a reduced use of antibiotics, and vii) Shiga toxin-producing Escherichia coli: prevalence, transmission, persistence, and factors that affect prevalence of this pathogen.