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2019 November Vol.32 No.6 ISSN 1598-8384

신진과학자

신진과학자 소개

양 정 은
양 정 은 (Jung Eun Yang)

세계김치연구소 E-mail : junge@wikim.re.kr

[학력]
  • 2007.03 – 2011.02

    수원대학교 신소재공학과, 학사

  • 2011.09 – 2013.08

    한국과학기술원 생명화학공학과, 석사

  • 2013.09 – 2017.02

    한국과학기술원 생명화학공학과, 박사

[경력]
  • 2017.02 – 2018.10

    한국과학기술원 생물공정연구센터, 박사 후 연구원

  • 2018.10 – 현재

    세계김치연구소 선임연구원

주요 연구 관심 분야 소개

  • 미생물 대사공학을 통한 유용 소재 대량 생산
  • 미생물 유전체 개량 기술 개발
  • 미생물을 이용한 환경정화 기술 개발
  • 유산균을 이용한 기능성소재 대량생산 기술 개발
  • 김치유래 미생물 대사조절 기술 및 고부가가치 화합물 생산 기술 개발

연구성과 - 논문

  • 1. Kim, H.K., Jeong, S.W., Yang, J. E*., Choi, Y.J. Highly efficient and stable removal of arsenic by live cell fabricated magnetic nanoparticles”, Int. J. Mol. Sci., 20(14): 3566 (2019) [Corresponding author]*
  • 2. Choi, I.S., Ko, S.H., Kim, H.M., Chun, H.H., Lee, K.H., Yang, J.E., Jeong, S., Park, H. W. “Shelf-life extension of freeze-dried Lactobacillus brevis WiKim0069 using supercooling pretreatment”, LWT-Food Sci. Technol.,112: 108230 (2019)
  • 3. Lee, C.H., Shim, H.E., Song, L., Moon, H.G., Lee, K., Yang, J.E., Song, H.Y., Choi, Y.J., Choi, D.S., Jeon, J. “Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in mice”, Chem. Commun., 55(4): 447-450 (2019) [Journal cover paper]
  • 4. Shim, H.E., Yang, J.E*, Jeong, S.W., Lee, C.H., Song, L., Mushtaq, S. Choi, D.S., Choi, Y.J., Jeon, J. “Silver nanomaterial-immobilized desalination systems for efficient removal of radioactive iodine species in water”, Nanomaterials, 8(9): 660 (2018) [Co-first author]*
  • 5. Mushtaq, S., Choi, M.H., Yang, J.E., Shim, H.E., Lee, S., Song, H.Y., Choi, Y.J., Jeon, J. “Technetium-99m-based simple and convenient radiolabeling of Escherichia coli for in vivo tracking of microorganisms”, J. Radioanal. Nucl. Chem., 317(2): 997-1003 (2018)
  • 6. Yang, J.E., Park, S.J., Kim, W.J., Kim, H.J., Kim, B.J., Lee, H., Shin, J.H, Lee, S.Y. "One-step fermentative production of aromatic polyesters from glucose by metabolically engineered Escherichia coli strains", Nat. Commun., 9(1): 79 (2018)  [BRIC 선정 2018 국내 Bio분야 연구성과 Top5]
  • 7. David, Y., Joo, J.C., Yang, J.E.*, Oh, Y.H., Lee, S.Y., and Park, S.J. "Biosynthesis of 2-hydroxyacid-containing polyhydroxyalkanoates by employing butyryl-CoA transferases in metabolically engineered Escherichia coli", Biotechnol. J., 12(11): 1-11 (2017) [Co-first author]*
  • 8. Mushtaq, S., Yun, S.J., Yang, J.E.*, Jeong, S.W., Shim, H.E., Choi, M.H., Park, S.H., Choi, Y.J. and Jeon, J. "Efficient and selective removal of radioactive iodine anions using engineered nanocomposite membranes", Environ. Sci. Nano, 4(11), 2157-2163 (2017) [Co-first author]*
  • 9. Jeong, S.W., Yang, J.E.*, Im, S., Choi, Y.J. "Development of Cre-lox based multiple knockout system in Deinococcus radiodurans R1", Korean J. Chem. Eng., 34(6): 1728-1733 (2017) [Co-first author]*
  • 10. Choi, M.H., Jeong, S.W., Shim, H.E., Yun, S.J., Mushtaq S., Choi D.S., Jang B.S., Yang, J.E., Choi, Y.J., Jeon, J. "Efficient bioremediation of radioactive iodine using biogenic gold nanomaterial-containing radiation-resistant bacterium, Deinococcus radiodurans R1", Chem. Commun., 53(28): 3937-3940 (2017)
  • 11. Yang, J.E., Kim, J.W., Oh, Y.H., Choi, S.Y., Lee, H., Park, A.-R., Shin, J., Park, S.J., and Lee, S.Y. "Biosynthesis of poly(2-hydroxyisovalerate-co-lactate) by metabolically engineered Escherichia coli", Biotechnol. J., 11(12): 1572-1585 (2016) [Journal cover paper]
  • 12. Choi, S.Y., Park, S.J., Kim, W.J., Yang, J.E., Lee, H., Shin, J., Lee, S.Y. "One-step fermentative production of poly(lactate-co-glycolate) from carbohydrates in Escherichia coli", Nature Biotechnol., 34(4): 435-440 (2016) [BRIC 선정 2016 국내 Bio분야 연구성과 Top5], [2017 국가연구개발사업 우수성과 100]
  • 13. Chae, C.G., Kim, Y.J., Lee, S.J., Oh, Y.H., Yang, J.E., Joo, J.C., Kang, K.H., Jang, Y.-A., Lee, H., Park, A.-R., Song, B.K., Lee, S.Y., Park, S.J., "Biosynthesis of poly(2-hydroxybutyrate-co-lactate) in metabolically engineered Escherichia coli", Biotechnol. Bioproc. Eng., 21: 169-174 (2016)
  • 14. Chung, H., Yang, J.E., Ha, J.Y., Chae, T.U., Shin, J.H., Gustavsson, M., Lee, S.Y. "Bio-based production of monomers and polymers by metabolically engineered microorganisms", Curr. Opin. Biotechnol., 36: 73-84 (2015)
  • 15. Park, S.J., Jang, Y.-A., Noh, W., Oh, Y.H., Lee, H., David, Y., Baylon, M.G., Shin, J., Yang, J.E., Choi, S.Y., Lee, S.H., Lee, S.Y., "Metabolic engineering of Ralstonia eutropha for the production of polyhydroxyalkanoates from sucrose", Biotechnol. Bioeng., 112:638–643 (2015)
  • 16. Park, S.J., David, Y., Baylon, M.G., Hong, S.H., Oh, Y.H., Yang, J.E., Choi, S.Y., Lee, S.H., Lee, S.Y., "Development of metabolic engineering strategies for microbial platform to produce bioplastics", Appl. Chem. Eng., 25(2): 134-141 (2014)
  • 17. Yang, J.E., Choi, Y.J., Lee, S.J., Kang, K.-H., Lee, H., Oh, Y.H., Lee, S.H., Park, S.J., and Lee, S.Y., "Metabolic engineering of Escherichia coli for biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) from glucose", Appl. Microbiol. Biotechnol., 98(1): 95-104 (2014)
  • 18. Yang, J.E., Choi, S.Y., Shin, J.H., Park, S.J. and Lee, S.Y., "Microbial production of lactate-containing polyesters", Microbial Biotechnol., 6(6): 621-636 (2013)
  • 19. Park, S.J., Jang, Y.-A., Lee, H., Park, A.-R., Yang, J.E., Shin, J., Oh, Y.H., Song, B.K., Jegal, J., Lee, S.H., and Lee, S.Y., "Metabolic engineering of Ralstonia eutropha for the biosynthesis of 2-hydroxyacid-containing polyhydroxyalkanoates", Metabolic Eng., 20: 20-28 (2013)
  • 20. Park, S.J., Kang, K.-H., Lee, H., Park, A.-R., Yang, J.E., Oh, Y.H., Song, B.K., Jegal, J., Lee, S.H., Lee, S.Y., "Propionyl-CoA dependent biosynthesis of 2-hydroxybutyrate containing polyhydroxyalkanoates in metabolically engineered Escherichia coli", J. Biotechnol., 165(2): 93-98 (2013)

연구성과-저서

  • 1. Park, S.J., Shin, J.H., Yang, J.E. and Lee, S.Y., "Synthetic biology of hydrophobic polymer production." Hydrocarbon and Lipid Microbiology Protocols. Springer, Berlin, Heidelberg (2015)

연구성과 - 특허

  • 1. Lee, S.Y., Yang, J.E., Park, S.J. “Method for Preparing Polyhydroxyalkanoates Using 2-Hydroxyisocaproate-CoA Transferase” PCT/KR2018/002305 (2018.02)
  • 2. Lee, S.Y. and Yang, J.E. “Preparing Method of 4-hydroxyphenyllactic Acid Using Variant Microorganism” Registered KR 10-1816100-0000 (2018.01)